SPOC Biosciences

Display technologies compress the sub-nanomolar space into a single bin, masking your most potent candidates. SPOC Biosciences resolves binding affinities down to 2 pM directly on-chip, across 1,152 variants at once. Unpack the tightest binders in your library with high-resolution SPR kinetics by measuring real dissociation curves without wash artifacts or coarse binning. https://lnkd.in/gkhZPMBr

Frustrated by fragmented experimental workflows? Traditional protein expression, purification and instrument analysis consume months of valuable R&D time. SPOC Biosciences unifies the entire process on a single on-chip library. Synthesize up to 1,152 folded proteins or antibodies directly on one biosensor chip and deliver high-resolution SPR binding kinetics in weeks, not months.

When engineering high-affinity binders, standard high-throughput screening often falls short. They flatten out your best leads or fails to resolve slow dissociation rates accurately. The SPOC platform solves this limitation. Resolve sub-nanomolar binding affinities across dense libraries on a single chip. Capture precise kinetic parameters (ka, kd, KD) for your top-performing variants without sacrificing throughput or sacrificing resolution. https://lnkd.in/gkhZPMBr

To build frontier AI models for drug discovery, you need ultra-high-resolution biological data. But microwell plates are holding you back. SPOC Biosciences brings semiconductor-style miniaturization and parallelization to deep-tech life sciences. Generate rich, decision-ready data stacks with up to 1,152 targets per chip running simultaneous quantitative and kinetic SPR assays.

Machine learning models are only as good as the biological datasets training them. Fragmented, low-throughput assays produce noisy data stacks that stall AI drug discovery. SPOC platform generates high-resolution, standardized datasets at scale. Synthesize and profile up to 1,152 folded proteins on a single chip to output uniform, rich kinetic matrices (ka, kd, KD) optimized for frontier AI model training.

Are your early screening assays missing your strongest therapeutic candidates? Coarse, low-resolution affinity data can cause high-affinity leads to mask each other or drop below the detection threshold. SPOC Biosciences delivers the high-fidelity resolution needed to differentiate between exceptionally tight binders early in the cycle. Move beyond simple yes/no binding answers or enrichment scores to precise, deep-characterization kinetics from day one. https://lnkd.in/gkhZPMBr