Genovis

Join Benqian Wei from Merck for our next GenovisWebinar: Advancing Biotherapeutic Characterization – HILIC-MS-Enabled Subunit-Level MAM. Benqian will show how FabRICATOR® subunit digestion combined with HILIC-MS improves separation and monitoring of critical PQAs in complex biotherapeutics – with case studies on IgG and Fc-fusion proteins. Relevant for analytical scientists, MS-based MAM in R&D and QC, CROs, and lab heads optimizing PQA monitoring. 📅 Thursday Nov 12 | 10 AM ET / 4 PM CET

Peptide-based MAM gives you detail – but at the cost of long sample preparation and LC-MS run times. On November 12, Benqian Wei from Merck shows how a HILIC-MS-based subunit-level MAM with FabRICATOR® lets you monitor multiple product quality attributes in a single assay – faster, with reproducible quantitative performance. You'll see: • Improved chromatographic separation of PTMs • N- and O-glycosylation, deamidation, oxidation and succinimide formation at the subunit level • Case studies on IgG and Fc-fusion proteins 📅 Thursday Nov 12 | 10 AM ET / 4 PM CET

Now from Genovis: TrypsINATOR™ + LysCERATOR™ in One Reagent LysCERATOR just got a "partner-in-digest" 🤩 The TrypsINATOR LysCERATOR Mix combines TrypsINATOR and LysCERATOR in a single reagent — Genovis's own take on dual-specificity digestion, built for even cleaner peptide pools from complex samples. And with minimal autoproteolysis, you get the added coverage without the background noise trypsin is known for! The result: up to 88% fully cleaved peptides in human cell lysates. Discover the TrypsINATOR LysCERATOR Mix 👉

Still struggling with missed cleavages at K–P sites? Let’s see how LysCERATOR™ stacks up against traditional Lys-C enzymes In head-to-head trastuzumab experiments, LysCERATOR™ outperformed standard Lys-C at challenging lysine–proline (K–P) sites. In what ways? • Higher Efficiency: Superior digestion at K–P sites. • Cleaner Results: Significantly fewer missed cleavages. • Better Mapping: Improved sequence coverage and reliability. Check out the trastuzumab K–P digestion data here 👉

How much are missed cleavages affecting your data? 🤔 LysCERATOR™ is designed to deliver high digestion efficiency and strong lysine specificity—helping you generate more informative peptide pools from complex samples. In HeLa lysates, it produced more unique peptides and a higher proportion of fully cleaved peptides compared to alternative Lys-C enzymes. Discover how LysCERATOR works on HeLa Cell Lysates 👉

Fresh from ASMS: New LysCERATORTM data is now available! 🌟🦈 Our latest poster highlights the versatility of LysCERATOR™ across a broad range of digestion conditions. Among the findings: efficient digestion under mildly acidic conditions (pH 5–6), supporting disulfide mapping workflows where preserving native disulfide linkages is important. 📄 Download the ASMS poster and explore the results for yourself! Find your LysCERATOR application here: https://lnkd.in/emKDiiPi