Cygnus Technologies, LLC

Understanding which HCPs remain from harvest to DS is critical for product quality. Explore how LC-MS delivers comprehensive profiling and precise, accurate quantification across your process.

Total HCP data alone can leave critical risks hidden. See how advanced LC-MS approaches provide deeper insight by identifying and quantifying individual HCPs.

Your DS needs more than luck! ☘ 🏆Cygnus' gold standard products and services are here to keep your manufacturing process on track. -Host cell protein (HCP), Protein A & other bioprocess impurity detection kits -Custom HCP antibody & assay development -HCP coverage analysis -LC-MS services for HCP identification and quantification Let's discuss your next project! https://lnkd.in/eq9nb9H9

Maximize sensitivity and specificity in host cell DNA quantification with AccuRes™. This all-in-one qPCR kit delivers reliable, robust detection across every stage of your bioprocess.

📊The data's better when they're together! While HCP ELISA remains the gold standard in HCP analysis, MS is a powerful orthogonal method that helps manufacturers gain a deeper understanding of the HCP profile during process development and in the final DS. ELISA tracks HCP clearance during process development 🤝AAE-MS helps qualify HCP ELISA as fit-for-purpose ELISA provides a quick glance into process efficiency 🤝 MS confirms HCP clearance ELISA is a critical tool for product lot release 🤝 MS is a critical tool for risk reduction Learn more: https://lnkd.in/ekDcfS6B

⚠️If you're still relying on 2D Western blotting for your HCP immunoassay qualification, you're using an outdated method that could be detrimental to your product quality and safety. ✅Antibody affinity extraction is a more reliable assay that is not only more sensitive and accurate, but can also identify specific host cell proteins captured by your HCP ELISA antibody when paired with MS technology. 📊Don't risk delays in your production process due to missed HCPs - gain a complete HCP coverage analysis with AAE. https://lnkd.in/eCWfziee #hostcellprotein #drugmanufacturing #biopharma