BioDuro

The people behind science are not only those who conduct or support research. They are also patients and families waiting for answers, supporting one another, and holding on to hope. ✨ Across the life sciences industry, research ultimately aims to improve patients’ health and quality of life and give them and their families more reasons to smile. That patient and family perspective is at the center of our latest feature in 𝙏𝙝𝙚 𝙋𝙚𝙤𝙥𝙡𝙚 𝘽𝙚𝙝𝙞𝙣𝙙 𝙩𝙝𝙚 𝙎𝙘𝙞𝙚𝙣𝙘𝙚 𝙨𝙚𝙧𝙞𝙚𝙨. It shares the story of scientist and father David Covini, his wife, Caroline, and their son Matteo, who lives with 𝗠𝗘𝗖𝗣𝟮 𝗱𝘂𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝘀𝘆𝗻𝗱𝗿𝗼𝗺𝗲. Following Matteo’s diagnosis, David and Caroline founded Dupmecp2 to connect families, make scientific information more accessible, and support research. Read their story and meet the smiles behind the science♥️ #RareDisease #MECP2 #ThePeopleBehindTheScience #BioDuro30Years

𝗧𝗵𝗶𝘀 𝗕𝗿𝗲𝗮𝘀𝘁 𝗖𝗮𝗻𝗰𝗲𝗿 𝗔𝘄𝗮𝗿𝗲𝗻𝗲𝘀𝘀 𝗠𝗼𝗻𝘁𝗵, 𝘄𝗲 𝗿𝗲𝗰𝗼𝗴𝗻𝗶𝘇𝗲 𝘁𝗵𝗲 𝗼𝗻𝗴𝗼𝗶𝗻𝗴 𝗻𝗲𝗲𝗱 𝗳𝗼𝗿 𝗻𝗲𝘄 𝗮𝗻𝗱 𝗺𝗼𝗿𝗲 𝗲𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁𝘀. Here, we’re sharing one example of how BioDuro’s Biology team supports research in this field. Our in vitro assay panel supports the evaluation of ERα-BRD4 RIPTACs, which are designed to bring ERα and BRD4 together and leverage ERα expression to selectively disrupt BRD4 function in breast cancer cells. The panel examines whether Erα-BRD4 complex formation is accompanied by the expected functional changes. Comparing growth inhibition in ER-positive and ER-negative models adds insight into potential selectivity, helping researchers interpret differences in compound activity and prioritize compounds for further study. Interested in learning more about our Biology team’s work in this area? Send us a message - [email protected] #BreastCancerAwarenessMonth #RIPTAC #DrugDiscovery #Biology

𝗛𝗼𝘄 𝗱𝗼 𝘆𝗼𝘂 𝗺𝗲𝗮𝘀𝘂𝗿𝗲 𝘁𝗵𝗲 𝘃𝗮𝗹𝘂𝗲 𝗼𝗳 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 𝗺𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝘄𝗵𝗲𝗻 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝗻𝗼 𝘀𝗶𝗺𝗽𝗹𝗲 𝘀𝗰𝗼𝗿𝗲𝗯𝗼𝗮𝗿𝗱? 🏀Years ago, Xianjing Yu played basketball as a point guard, reading the whole court, anticipating what came next, and keeping the team moving. Today, as 𝗦𝗲𝗻𝗶𝗼𝗿 𝗗𝗶𝗿𝗲𝗰𝘁𝗼𝗿 𝗼𝗳 𝗣𝗿𝗼𝗷𝗲𝗰𝘁 𝗠𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗮𝘁 𝗕𝗶𝗼𝗗𝘂𝗿𝗼, she brings that same wider view to drug development: putting unexpected changes on the table, understanding what lies behind different positions, and helping teams make decisions with the whole program in view. 🔗See what the scoreboard doesn’t show. #BioDuro30Years #ProjectManagement #DrugDevelopment #ThePeopleBehindTheScience

🧬Service Spotlight: Oligonucleotide therapeutics continue to gain momentum, with more products reaching the market and pipelines expanding across targets and indications. To support this growing field, BioDuro builds on its established small-molecule discovery experience to deliver an integrated oligonucleotide discovery platform that connects specialized siRNA design, oligo chemistry and conjugation, biological evaluation, and oligo-specific bioanalysis. Whether you’re exploring new oligonucleotide candidates or advancing promising leads, download the flyer for a closer look at the platform: https://lnkd.in/eYP9-dHq #Oligonucleotides #siRNA #DrugDiscovery #DMPK #Biology #DidcoveryChemistry

Visit the company page for BioDuro

Your Trusted partner of CRDMO services