Atrandi Biosciences

Screen a million enzyme variants on function. Or pull a strain-level genome out of a community without culturing it. Two technologies, one webinar. Droplet screening on Onyx and Styx, and single-cell genomics with Semi-Permeable Capsules. Three sessions.

Musculoskeletal cancers carry genetic markers that tell clinicians how serious a case is. What they can't yet tell us is why. As Adam Cribbs, professor at the University of Oxford, puts it: tying a specific translocation to a specific change in gene expression, visible within a single tumour cell, would be a significant step toward understanding what is actually driving disease in individual patients. In our second Scientific Spotlight article, Adam takes us from bulk sequencing and its uncomfortable averages, to the hard tissues the field kept skipping, to the single-cell workflows being built to answer questions current techniques simply can't. Full story in the comments 👇 Thank you to Prof. Adam Cribbs and the Cribbs Group at the University of Oxford for sharing their story with us. #Atrandi #AtrandiBiosciences #ScientificSpotlight #SPC #OxfordUni

Multi-step single-cell workflows are where droplet-based approaches start to show their limits. Prof. Jeroen Lammertyn and Dr. Karen Ven at KU Leuven found a way forward. Semi-Permeable Capsules (SPCs) were not a replacement for droplets, but the missing block that made complex protocols possible. Twenty years of building tools other researchers can trust. See how their thinking evolved.

Plates or droplets? For single-cell work, that's usually meant trading flexibility for scale, or scale for flexibility. Semi-Permeable Capsules (SPCs) give you both: multi-step chemistry on tens of thousands of single cells at once, in one workflow. See how capsules compare to plates and droplets. Swipe through, then explore what they could do for your research.

For years, droplets carried Prof. Jeroen Lammertyn's lab at KU Leuven through single-cell biology. Until multi-step protocols became difficult to manage in droplets alone. That's where Semi-Permeable Capsules came in – not a replacement, but a missing block. In our first Scientific Spotlight article, Prof. Jeroen Lammertyn and Dr. Karen Ven take us from pears (yes, pears) to microwells, to droplets, to capsules. Twenty years of building tools other scientists can actually trust. Full story in the comments 👇 First in our Scientific Spotlight series. More are already on the way, so stay tuned. Thank you to Prof. Jeroen Lammertyn, Dr. Karen Ven, and KU Leuven for sharing their story with us. #Atrandi #AtrandiBiosciences #ScientificSpotlight #KULeuven #droplets #SPC

What actually happens inside a cell when a virus infects? For most of virology's history, we couldn't answer that properly. Single-cell genomics is changing that, and it is showing us what was invisible before. 🔽 Read full article down below 🔽 👉 Be sure to subscribe to #AtrandiPulse to receive notifications when the latest edition is released: https://lnkd.in/d5bYdFZZ #Atrandi #AtrandiBiosciences #singlecell #SPC #viruses #COVID