Twist Bioscience

An off the shelf panel reflects someone else's priorities. When your targets, population or sample type don't fit, you sequence what you don't need and miss what you do. Twist custom NGS panels are designed around your research. Our team works through the design with you, and you can add content to an existing panel as your questions change. Start a design and talk it through with a Twist scientist.

PCR can skew what your genome data shows. Twist PCR Free WGS Library Prep skips amplification entirely, with high efficiency ligation and consistent insert sizes from 300 ng down to 37.5 ng of input. Multiplex up to 1,536 samples per run.

IgG production and full characterization (binding affinity, epitope binning, developability profiling) delivered together by one US-based team. No vendor hand-offs, no gaps, no surprises. One workflow from sequence to decision-ready data.

6,000+ IgGs per week. 20+ assay types. Structured, characterization-rich datasets configured for your pipeline and delivered when your model needs them. Built for teams who need validation data at the pace their models demand.

Solid tumor research rarely fits a fixed panel. Your tumor types, your targets and your sample population all shape what you need to see. The Twist Oncology DNA CGP Panel covers 560 genes across all major tumor types and identifies SNVs, indels, CNVs, select fusions, TMB and MSI. Add your own content and keep it in one workflow with Twist library prep and target enrichment.

Gene expression is only part of the story. This tech note shows how exon aware RNA capture profiles expression and identifies novel fusions in one workflow. Download it free.